Cardiovascular disease 

Research has concluded that vitamin D deficiency is an independent risk factor for cardiovascular disease (CVD), reinforcing its importance as a public health problem.⁽¹⁾⁽⁴⁾

New scientific evidence has, for the first time, concluded that vitamin D deficiency can be seen as an independent risk factor of atherosclerosis and demonstrated how vitamin D3 supplementation can protect against CVD.⁽¹⁾ A recent study demonstrated that in contrast to healthy individuals, otherwise healthy young individuals with vitamin D deficiency have signs of endothelial dysfunction, an early marker of atherosclerosis.⁽¹⁾

In addition to this, the researchers for the first time demonstrate that the endothelial dysfunction responds to treatment with vitamin D3 ensuring 25-Hydroxyvitamin D concentrations above 75-80 nmol/L.⁽¹⁾ This research presents significant justification to investigate vitamin D status in patients with cardiovascular disease, as recently suggested for patients with hypertension.⁽²⁾

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